Cytokeratin, Acidic (Type I or LMW) MBS438053 from MyBioSource.com

Product Specs
ItemCytokeratin, Acidic (Type I or LMW)
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS438053
Quantity0.1 mg
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistology (IH)
Conjugate/TagUnconjugated
ReactivityHuman, Monkey, Cow, Dog, Rabbit, Mouse, Rat, Chicken, Turtle
TargetCytokeratin
IsotypeIgG1
Molecular Weight40-57kDa
CloneAE-1
HostMouse
ImmunogenThis MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer
NCBI Full Gene Namekeratin 10, type I
NCBI Gene AliasesKPP, K10, BIE, CK10, BCIE, EHK
ClonalityMonoclonal